- Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) Antibody
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- MBS4380085
- 0.02 mg (With BSA & Azide at 0.2mg/ml)
- Monoclonal
- Human. Others not known
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
- Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
- Mouse
- 78-85kDa
- Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR)
- luteinizing hormone/choriogonadotropin receptor
- LCGR, LGR2, LHRHR, ULG5, HHG, LHR, LH/CGR, LSH-R, LH/CG-R
- Unconjugated
- IgG1 kappa
- LHCGR/1415
Specifications/Features
Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women